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KMID : 0367320080190020072
Journal of the Korean Academy of Child and Adolescent Psychiatry
2008 Volume.19 No. 2 p.72 ~ p.82
Non-Stimulant Medications in the Treatment of Attention-Deficit Hyperactivity Disorder
Hwang Jun-Won

Abstract
The aim of this paper is to evaluate the use of non-stimulants, including atomoxetine, bupropion and modafinil, as alternative approaches to the treatment of children with attention-deficit hyperactivity disorder. A comprehensive review of the empirically based literature regarding the efficacy and the safety of the non-stimulants was performed. There is a large and increasing body of data supporting the efficacy and the safety of non-stimulants. Although the treatment effect sizes for non-stimulants may be smaller than those for stimulants, non-stimulants alone have been shown to be effective in the treatment of attention-deficit hyperactivity disorder as well as several comorbidities. These results suggest that non-stimulants are effective in the treatment of attention-deficit hyperactivity disorder. Further studies are needed to improve our understanding of alternative pharmacological medications in the treatment of attention-deficit hyperactivity disorder.
KEYWORD
Attention-Deficit Hyperactivity Disorder, Atomoxetine, Bupropion, Modafinil
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